Fish-oil supplementation induces antiinflammatory gene
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1 p. Powered by Pure, Scopus & Elsevier Fingerprint Engine 2006-08-01 Thus Muller cell functions include: Supplying endproducts of anaerobic metabolism (breakdown of glycogen) to fuel aerobic metabolism in the nerve cells. They mop up neural waste products such as carbon dioxide and ammonia and recycle spent amino acid … Muller cells provide homeostatic and metabolic support for retinal neurons, like the ganglions and starburst amacrines we map in Eyewire. They are retinal glial cells that wrap around the cells that form capillaries, endothelial cells and pericytes, and constitute the majority of … Glaucoma is one of the leading causes of blindness, and there is an ongoing need for new therapies. Recent studies indicate that cell transplantation using Müller glia may be beneficial, but there is a need for novel sources of cells to provide therapeutic benefit. Bergmann glial cells assist with the migration of granule cells, guiding the small neurons from the external granular layer down to the internal granular layer along their extensive radial processes. Besides their role in early development of the cerebellum, Bergmann glia are also required for synaptic pruning.
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Eberhardt C, Amann B, Stangassinger M, Hauck SM, Deeg CA. Isolation, characterization and establishment of an equine retinal glial cell line: a prerequisite to investigate the physiological function of muller cells in the retina. J Anim Physiol Anim Nutr (Berl) 2011; 96:260–269. doi: 10.1111/j.1439-0396.2011.01147.x. These data thus led us to propose a model in which YAP function in Müller cells would be necessary for ensuring the maintenance of Müller cell homeostasis and preserving cone integrity (Fig. 8). Although we know that Müller glia can function as retinal stem cells following injury, no one has tested whether damage specifically targeted to retinal ganglion cells, as occurs in glaucoma, is sufficient to stimulate Müller glia-dependent retinal ganglion cell regeneration.
IJMS Free Full-Text Fructose and Uric Acid: Major Mediators
By mediating transcellular ion, water, and bicarbonate transport, Müller cells control the composition of the extracellular space fluid. Müller cells provide trophic and anti-oxidative support of photoreceptors Müller cells are the principal glial cells of the retina, assuming many of the functions carried out by astrocytes, oligodendrocytes and ependymal cells in other CNS regions.
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They fulfill a wide range of physiological functions to support the functioning and survival of retinal neurons (11). Mueller cells are important for glutamate metabolism (in the uptake of the transmitter released by photoreceptors), as well as for the storage of calcium ions. Damage to glial cells, e.g. by the ammonia toxicity of alcohol syndrome (caused by severe toxic hepatic damage), produces marked changes in the ERG (Eckstein et al 1997).
PMC 4445728. PMID 25848755. Guo
Extract Improves Both NK and γδ-T Cell Function and Reduces the Severity of Müller et al., “Effect of Broccoli Sprouts and Live Attenuated Influenza Virus on
Schmitt, E.; Germann, T.; Goedert, S.; Hoehn, P.; Huels, C.; Koelsch, S.; Kühn, R.; Müller, W.; Palm, N. (1994-11-01). "IL-9 production of naive CD4+ T cells
Ralf Haas (2011). "Interaction of tumor cells with the microenvironment". Cell Communication and Signaling.
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Delabie J, Ott G, Muller-Hermelink HK, Campo E, Braziel RM, Jaffe ES, Pan Z, Biological process, Molecular function, Disease Mucus-secreting cells, Muller glia cells, Pancreatic endocrine cells, Paneth cells, Peritubular cells, Proximal ERK5 functionally links ALK signaling to MYCN expression in Goldring, J. Müller, M. J. Cross, ERK5: Structure, regulation and function. Cell. av T Hatzihristidis · 2015 · Citerat av 9 — In the light of the work by Muller et al.
There is growing evidence that these mutant p53s have both lost wild-type p53 tumor suppressor activity and gained functions that help to contribute to malignant progression. Understanding the functions of mutant p53 will help in the development of new therapeutic
Glia-Neuron Interactions in the Retina Can Be Studied in Cocultures of Muller Cells and Retinal Ganglion Cells. Research output: Contribution to journal › Journal article › Research › peer-review
Muller cells a key cell in preventing age-related vision loss (c) Duke: Their findings show that hUTC treatment preserves the function of a retinal cell called the Müller glia in rats with degenerative vision loss. The research has been published online in the Journal of Neuroscience.
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Pancreatic extracellular communication - Chalmers
Thus, Müller cells are responsible for a stable metabolic dialogue in the inner retina and their crucial role in supporting retinal neurons is indisputable. Müller cells, the major type of glial cells in the retina, are responsible for the homeostatic and metabolic support of retinal neurons. By mediating transcellular ion, water, and bicarbonate transport, Müller cells control the composition of the extracellular space fluid. Müller cells provide trophic and anti‐oxidative support of photoreceptors and neurons and regulate the tightness of the blood‐retinal barrier. In their stead, the Müller cell serves as the principal glial cell of the retina. It performs many of the functions subserved by astrocytes, oligodendrocytes and ependymal cells in other regions of the CNS. Müller cells, the major type of glial cells in the retina, are responsible for the homeostatic and metabolic support of retinal neurons.
IJMS Free Full-Text Fructose and Uric Acid: Major Mediators
Here, we review evidence that indicate that these two cell populations exchange functionally significant signals under uninjured conditions and during retinal inflammation. För att en T-cell ska känna igen ett antigen krävs en antigenpresenterande cell (APC). T-celler tillhör immuncelltypen lymfocyter, och kan skiljas från andra lymfocyter som B-celler och NK-celler, genom att de har en särskild receptor på sin cellyta. Flera olika undergrupper av T-celler har upptäckts, var och en med en särskild funktion. The CELL function returns information about the formatting, location, or contents of a cell.
During retinal injury gliotic Similarly, in JR, the Müller cells expressed less intense GFAP, CNTF and FGF2 staining compared to AR. Our results suggest that in JR the degree of retinal av D RIBEIRO · 2018 — pancreatic islets, and generation of stem cell-derived pancreatic beta cells (Paper V). response, β cells increase insulin production but overall β cell function and mass  C. Goldsbury, K. Goldie, J. Pellaud, J. Seelig, P. Frey, S.A. Muller, The Fovea: Structure, Function, Development, and Disease summarizes the current In the last part, the roles of Muller cells and astrocytes in the pathogenesis Magnitude and Functional Profile of the Human CD4(+) T Cell Response Moretta L, Mosmann Tr, Muller S, Multhoff G, Munoz Le, Munz C, Nakayama T, Nasi Our studies include phenotypic and functional assessments of NK cells with a Marschall Hu, Marzioni M, Melum E, Milkiewicz P, Müller T, Pares A, Rupp C, av M Bouwens · 2009 · Citerat av 343 — fatty acids can have beneficial effects on human immune cells, such as peripheral blood mononuclear cells (PBMCs). Michael Müller,. av X Huang · 2018 · Citerat av 30 — (2,5) Importantly, pretreatment of cancer cells with salinomycin was also data indicate that the principal function of salinomycin is ionophore activity in the Debieu, Sebastian Müller, Tatiana Cañeque, Raphaël Rodriguez. Microfluidic, label-free enrichment of prostate cancer cells in blood based on acoustophoresis PB Muller, M Rossi, AG Marin, R Barnkob, P Augustsson, T Laurell, . does not impact survival or function of microglia, leukocytes or tumor cells.